In our prospective cohort study, our clinical research group from University of Alberta and Mount Sinai Hospital/University of Toronto found that active IBD during trimester one is correlated with adverse post-neonatal outcomes, particularly decreased infant weight and height up to 6 months of age.
This suggests disease control in first trimester is essential for optimizing infant growth and post-neonatal outcomes.
IBD be well controlled before the patient tries to conceive and maintained in remission throughout pregnancy for best maternal and infant outcomes.
Post-neonatal Outcomes of Infants Born to Women with Active Trimester One Inflammatory Bowel Disease: A Pilot Study. R Wu, P Tandon, L Ambrosio, G Dunsmore, N Hotte, L Dieleman, S Elahi, K Madsen, V Huang. Dig Dis Sci 2022 Feb 24. doi: 10.1007/s10620-022-07430-x. Online ahead of print.